Package: LocalControl Type: Package Title: Nonparametric Methods for Generating High Quality Comparative Effectiveness Evidence Version: 1.1.7 Date: 2026-03-03 Authors@R: c( person(given = "Nicolas R.", family = "Lauve", role = "aut", comment=c(ORCID="0000-0002-9348-0319")), person(given = "Stuart J.", family = "Nelson", role = "aut", comment=c(ORCID="0000-0002-8756-0179")), person(given = "S. Stanley", family = "Young", role = "aut", comment=c(ORCID="0000-0001-9449-5478")), person(given = "Robert L.", family = "Obenchain", role = "aut", comment=c(ORCID="0000-0002-8395-1666")), person(given = "Melania", family = "Pintilie", role = "ctb"), person(given = "Martin", family = "Kutz", role = "ctb"), person(given = "Christophe G.", family = "Lambert", role = c("aut","cre"), email = "cglambert@salud.unm.edu", comment=c(ORCID="0000-0003-1994-2893"))) Description: Implements novel nonparametric approaches to address biases and confounding when comparing treatments or exposures in observational studies of outcomes. While designed and appropriate for use in studies involving medicine and the life sciences, the package can be used in other situations involving outcomes with multiple confounders. The package implements a family of methods for non-parametric bias correction when comparing treatments in observational studies, including survival analysis settings, where competing risks and/or censoring may be present. The approach extends to bias-corrected personalized predictions of treatment outcome differences, and analysis of heterogeneity of treatment effect-sizes across patient subgroups. For further details, please see: Lauve NR, Nelson SJ, Young SS, Obenchain RL, Lambert CG. LocalControl: An R Package for Comparative Safety and Effectiveness Research. Journal of Statistical Software. 2020. p. 1–32. Available from . License: Apache License 2.0 | file LICENSE URL: https://github.com/OHDSI/LocalControl BugReports: https://github.com/OHDSI/LocalControl/issues LazyData: TRUE LinkingTo: Rcpp Imports: Rcpp, gss, cluster, lattice, stats, graphics Suggests: colorspace, RColorBrewer, data.table, ggplot2, gridExtra, rpart, rpart.plot, xtable, R.rsp VignetteBuilder: R.rsp RoxygenNote: 7.3.2 Encoding: UTF-8 NeedsCompilation: yes Depends: R (>= 3.0.0) Maintainer: Christophe G. Lambert Repository: https://ohdsi.r-universe.dev Date/Publication: 2026-03-03 22:46:46 UTC RemoteUrl: https://github.com/ohdsi/localcontrol RemoteRef: HEAD RemoteSha: 8ea9d1043d1ea0e56144cf5ed4da5152e42a7b77 Packaged: 2026-06-01 09:49:17 UTC; root Author: Nicolas R. Lauve [aut] (ORCID: ), Stuart J. Nelson [aut] (ORCID: ), S. Stanley Young [aut] (ORCID: ), Robert L. Obenchain [aut] (ORCID: ), Melania Pintilie [ctb], Martin Kutz [ctb], Christophe G. Lambert [aut, cre] (ORCID: )