Package: EmpiricalCalibration Type: Package Title: Routines for Performing Empirical Calibration of Observational Study Estimates Version: 3.1.4 Date: 2025-02-14 Authors@R: c( person("Martijn", "Schuemie", , "schuemie@ohdsi.org", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-0817-5361")), person("Marc", "Suchard", role = c("aut"), comment = c(ORCID = "0000-0001-9818-479X")) ) Maintainer: Martijn Schuemie Description: Routines for performing empirical calibration of observational study estimates. By using a set of negative control hypotheses we can estimate the empirical null distribution of a particular observational study setup. This empirical null distribution can be used to compute a calibrated p-value, which reflects the probability of observing an estimated effect size when the null hypothesis is true taking both random and systematic error into account. A similar approach can be used to calibrate confidence intervals, using both negative and positive controls. For more details, see Schuemie et al. (2013) and Schuemie et al. (2018) . VignetteBuilder: knitr Depends: R (>= 3.5.0) Imports: ggplot2 (>= 2.0.0), gridExtra, methods, rlang, Rcpp Suggests: knitr, markdown, rmarkdown, testthat, Cyclops, survival, Sequential License: Apache License 2.0 LinkingTo: Rcpp NeedsCompilation: yes URL: https://ohdsi.github.io/EmpiricalCalibration/, https://github.com/OHDSI/EmpiricalCalibration BugReports: https://github.com/OHDSI/EmpiricalCalibration/issues RoxygenNote: 7.3.2 Encoding: UTF-8 Repository: https://ohdsi.r-universe.dev Date/Publication: 2025-02-14 17:01:50 UTC RemoteUrl: https://github.com/ohdsi/empiricalcalibration RemoteRef: HEAD RemoteSha: 03d4747fd805e92744d0bcaf603f4c2d0b13370b Packaged: 2026-06-24 01:09:24 UTC; root Author: Martijn Schuemie [aut, cre] (ORCID: ), Marc Suchard [aut] (ORCID: )